Research

Geraint undertook his Wellcome Trust Clinical Research Fellowship at the University of Birmingham (Immunoregulation of Acquired Ocular Immunobullous Disease; http://etheses.bham.ac.uk/3235/), gaining his PhD in 2012.  He observed that progressive scarring of the membranes surrounding the eye (the conjunctiva) in Ocular Mucous Membrane Pemphigoid (OcMMP) occurred in the absence of clinically identifiable inflammation. He developed a novel non-invasive means of characterising ocular surface inflammatory cells in both health and disease and used this to determine that the conjunctiva was characterised by an increase in a population of cells called neutrophils and associated with progression of scarring.

He subsequently worked as a clinical lecturer at the University of Birmingham from 2012 to 2014. He combined this role with fellowship training in cornea and external disease. During his tenure he was responsible for teaching medical students and his research interests included:

  • Established an international steering committee towards developing an Ocular Surface Disease Index Scoring System (OSD-ISS) to determine activity and damage indices.
  • Validating image analysis software for quantifying corneal nerve damage in Herpes Simplex Keratitis (HSK).
  • Improving the understanding of how the immune system recognises and regulates our responses to HSK.
surgical knot

While undertaking his international fellowship at the Singapore National Eye Centre (2014-2015), he worked with Prof Jod Mehta at the Singapore Eye Research Institute. His research focused on the application of femtosecond laser platforms in improving anterior segment surgery including:

  • Real-time intra-ocular pressure measurement during femtosecond assisted laser cataract surgery (FLACS) and the effects of corneal thickening and energy alteration in FLACS.
  • The efficacy and safety profile of small incision lenticule extraction (SMILE) and LASIK.

Geraint is an honorary senior lecturer at the Institute for Inflammation and Ageing, University of Birmingham. His current research interests include methods to detect inflammation and progressive scarring on the ocular surface, how the immune system responds to infection and how improved measurement such as imaging systems can help detect these responses. His further interests include the role of lasers in improving outcomes in cataract and corneal surgery. He speaks widely to audiences in the UK and abroad and is a reviewer for numerous ophthalmic and scientific journals.

Invited Speaker

  • _ _ 1st Dec 2017

    Ocular Surface Healing.

    MCLOSA 2017, Gloucester Millennium Hotel, London

  • _ _ 1st Nov 2017

    Prokera “my experience”.

    Scope Ocular Surface Roadshow, Hotel Indigo Birmingham

  • _ _ 4th Feb 2017

    The Management of Ocular Toxic Epidermal Necrolysis. Thea Cornea Day II.

    Think Tank at Millenium Point, Birmingham

  • _ _ 19th Oct 2016

    Low Energy, High Repetition Femtosecond Lasers. What do they have to offer?

    Royal Liverpool University Hospital University of Liverpool

  • _ _ 19th Oct 2016

    Investigating the role of immunity in chronic ocular surface disease.

    University of Liverpool

  • _ _ 12th Sep 2016

    LDV Z8 femtosecond laser lens in capsulotomy. Williams GP and Mehta JS

    Ziemer User Group Meeting, ESCRS, Copenhagen

  • _ _ 31st Aug 2016

    Herpes Simplex Keratitis.

    Royal Liverpool University Hospital University of Liverpool

  • _ _ 22nd Nov 2014

    Ziemer User Group Meeting. The effects of the Ziemer LDV Z8 on intra-ocular pressure during cataract surgery.

    Four Seasons Hotel, Chiang Mai, Thailand

  • _ _ 3rd March 2014

    Cicatricial Conjunctivitis: Getting to the root of the problem.

    Oxford Deanery Regional Teaching, John Radcliffe Hospital, Oxford

  • _ _ 28th Feb 2014

    Herpes Simplex Keratitis under the microscope.

    MOS Meeting, Wolverhampton

  • _ _ 19th Apr 2013

    Mucous Membrane Pemphigoid.

    Patient Engagement Day, Moorfields Eye Hospital London

  • _ _ 16th May 2012

    Sub-clinical inflammation in Mucous Membrane Pemphigoid: Can 'hidden' neutrophils predict disease progression?

    Ophthalmology Showcase Session at the 2012 Royal College of Ophthalmologists Congress, Liverpool

  • _ _ 24th May 2011

    Ocular Surface Impression Cytology: What else does it have to offer?

    Academic Ophthalmology & Translational Research Session. Royal College of Ophthalmologists Congress, Birmingham

  • _ _ 28th Oct 2008

    Ocular Mucous Membrane Pemphigoid: Late Arrivals.

    The Midland Ophthalmological Society and Pantheo Joint Scientific Meeting, Limassol, Cyprus

  • _ _ 28th Oct 2008

    Toxic Epidermal Necrolysis: The perfect storm

    The Midland Ophthalmological Society and Pantheo Joint Scientific Meeting, Limassol, Cyprus

  • _ _ 11th Sep 2006

    Horner Syndrome. Royal College Regional Symposium: Nerves and Orbits.

    Royal Glamorgan Hospital, Llantrisant

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